Preimplantation Genetic Testing

PGD/PGS

What is PGT?

Preimplantation Genetic Testing is a procedure used prior the implantation to detect and prevent the transmission to the offspring of serious diseases caused by genetic and chromosomal alterations in embryos, to ensure that children are born free from hereditary diseases.

Preimplatation Genetic Diagnosis (PGD)

When one or both parent(s) are carriers of a genetic condition (gene mutation or unbalanced chromosomal rearrangement), a genetic diagnostic can be performed to determine whether that condition has been transmitted to the embryo.

Preimplatation Genetic Screening (PGS)

 
 

GENDER SELECTION

PGD has also been used for the purpose of gender selection

 

It can be used to detect which embryos are XX or XY. The desired embryos can be placed into the uterus to achieve pregnancy.

 

PGD is the only method for gender selection that is close to 100% accurate.

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    How does PGT work?

    Preimplantation Genetic Testing (or PGT) is a test which is performed after IVF is completed, when the oocytes have been fertilized and the embryos start dividing.

     

    A genetic test can be carried out once the embryo has reached the 8-cell stage (around the 3rd day of development), by removing a single cell (blastomere biopsy). Then, the embryo is returned to the incubator for further growth.

     

    However, it is recommended to perform the biopsy once embryos have become blastocysts (day 5-6). By the 5th day of development, the embryos will have divided into approximately 100 cells and have formed the outer layer that will eventually become the placenta. At this stage, a trophoblast biopsy can be performed, by removing a few cells from the outer layer. This procedure does not affect the embryo’s quality or ability to implant.